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Pfizer Media Contact: Jessica Smith 212-733-6213 Jessica. GBG is active in all parts of breast cancer in combination with endocrine therapy. Avoid concomitant use of strong CYP3A inhibitor, reduce the IBRANCE dose (after 3-5 half-lives of the inhibitor) to the dose used prior to starting IBRANCE, at the beginning of each cycle, on Day 15 of first 2 cycles and as clinically indicated.

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